Emergency services were called to Ellis Road, Rous, about 15km from Ballina, around 3.45pm yesterday (June 19) following reports of a head-on collision.
A grey Mazda 3 sedan was travelling west along Ellis Road when the driver lost control and veered onto the wrong side of the road, colliding with a Mazda BT50 4WD travelling east.
A 34-year-old man from Uralba, the driver and sole occupant of the sedan, died at the scene.
The 27-year-old female driver of the 4WD was taken to Lismore Base Hospital for mandatory blood and urine testing.
A child under two, the only passenger in the 4WD, suffered minor cuts and was also taken to hospital for precautionary checks.
Police are urging anyone who witnessed the crash to contact Lismore Police or Crime Stoppers on 1800 333 000.