The Westpac Life Saver Rescue Helicopter was tasked during the night (Sunday, March 18) to a single-vehicle collision on River Drive South Ballina.
A car in which three people were travelling had left the road and collided with a tree.
It was reported that the 31-year-old female occupant of the vehicle was trapped by compression.
She was released by local SES and transported by helicopter to Gold Coast University Hospital in a critical condition suffering multiple injuries.
Two male occupants were transported by road ambulance to Lismore Base Hospital in a stable condition.