Emergency services were called to a unit on Kingscliff Street, Kingscliff, last night following reports a man had been stabbed.
A man remains in a serious condition in hospital following the malicious wounding at about 10.40pm Sunday evening.
Officers from Tweed/Byron Police District attended and located a 56-year-old man with multiple stab wounds to his head, chest, and abdomen.
Initial inquiries suggest the man was injured following an altercation with another man inside the unit.
The man was treated at the scene by NSW Ambulance Paramedics before being taken to Gold Coast University Hospital to undergo surgery.
Police seized a hunting knife at the location which will be forensically examined.
No arrests have been made.
Police are urging anyone with information to contact police via Crime Stoppers: 1800 333 000 or https://nsw.crimestoppers.com.au. Information is treated in strict confidence. The public is reminded not to report crime via NSW Police social media pages.